https://www.cell.com/molecular-plant/issue?pii=S1674-2052%2823%29X0004-5
서울대학교 서필준 교수님 연구실에서 의뢰하신 논문커버아트가 front cover로 선정되었습니다. 축하드립니다.
Mar 04, 2024, Volume 17Issue 3p363-508
The cover image illustrates a paradox of callus proliferation during in vitro plant regeneration. Hypoxic microenvironments resulted from active callus proliferation during the in vitro plant regeneration process intrinsically inhibit callus regeneration competence. Low oxygen levels in callus (shown in red) activate the RAP2.12 protein, which promotes salicylic acid biosynthesis to inhibit callus cell pluripotency. Given that continuous cell proliferation is essential for pluripotency maintenance, cell proliferation-induced hypoxia would be an unavoidable intrinsic limitation for tissue culture. This bottleneck can be overcome by hyperoxia treatment (i.e., excess supply of oxygen), providing an opportunity to increase plant tissue culture efficiency. Image by Pil Joon Seo.
https://www.cell.com/molecular-plant/issue?pii=S1674-2052%2823%29X0004-5
서울대학교 서필준 교수님 연구실에서 의뢰하신 논문커버아트가 front cover로 선정되었습니다. 축하드립니다.
Mar 04, 2024, Volume 17Issue 3p363-508
The cover image illustrates a paradox of callus proliferation during in vitro plant regeneration. Hypoxic microenvironments resulted from active callus proliferation during the in vitro plant regeneration process intrinsically inhibit callus regeneration competence. Low oxygen levels in callus (shown in red) activate the RAP2.12 protein, which promotes salicylic acid biosynthesis to inhibit callus cell pluripotency. Given that continuous cell proliferation is essential for pluripotency maintenance, cell proliferation-induced hypoxia would be an unavoidable intrinsic limitation for tissue culture. This bottleneck can be overcome by hyperoxia treatment (i.e., excess supply of oxygen), providing an opportunity to increase plant tissue culture efficiency. Image by Pil Joon Seo.