https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202470077
고려대학교 김동휘 교수님 연구실에서 의뢰하신 저널커버가 advanced science의 front cover로 채택되었습니다. 축하드립니다.
Selective Suppression of Integrin-Ligand Binding by Single Molecular Tension Probes Mediates Directional Cell Migration (Adv. Sci. 14/2024)
Seong-Beom Han, Geonhui Lee, Daesan Kim, Jeong-Ki Kim, In-San Kim, Hae-Won Kim, Dong-Hwee Kim
Focal Adhesion Kinase Phosphorylation
In article number 2306497, Dong-Hwee Kim and co-workers report a novel method for selectively controlling a molecular binding force between intracellular protein integrin and extracellular matrix ligand protein in a pN scale, using a rupture force of double strand DNA. They demonstrate such a miniscule change of binding force can lead directional cell migration by phosphorylation of focal adhesion kinase (FAK).
https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202470077
고려대학교 김동휘 교수님 연구실에서 의뢰하신 저널커버가 advanced science의 front cover로 채택되었습니다. 축하드립니다.
Selective Suppression of Integrin-Ligand Binding by Single Molecular Tension Probes Mediates Directional Cell Migration (Adv. Sci. 14/2024)
Seong-Beom Han, Geonhui Lee, Daesan Kim, Jeong-Ki Kim, In-San Kim, Hae-Won Kim, Dong-Hwee Kim
Focal Adhesion Kinase Phosphorylation
In article number 2306497, Dong-Hwee Kim and co-workers report a novel method for selectively controlling a molecular binding force between intracellular protein integrin and extracellular matrix ligand protein in a pN scale, using a rupture force of double strand DNA. They demonstrate such a miniscule change of binding force can lead directional cell migration by phosphorylation of focal adhesion kinase (FAK).